Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm...
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
In echinoderm mitochondria, the codon AAA encodes asparagine instead of lysine. A newly identified nucleoside modification, hydroxy-
N
6
-threonylcarbamoyladenosine (ht
6
A), is found adjacent to the anticodon in mt-tRNA
Lys
and prevents mt-tRNA
Lys
from misreading AAA as lysine.
The genetic code is not frozen but stil...
Alternative Titles
Full title
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1926979990
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1926979990
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3449
