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Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact...

Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1928513223

Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products

About this item

Full title

Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Analytical and bioanalytical chemistry, 2017-10, Vol.409 (26), p.6057-6067

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Capillary zone electrophoresis (CZE) is a powerful tool that is progressively being applied for the separation of monoclonal antibody (mAb) charge variants. Mass spectrometry (MS) is the desired detection method concerning identification of mAb variants. In biopharmaceutical applications, there exist optimized and validated electrolyte systems for...

Alternative Titles

Full title

Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1928513223

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1928513223

Other Identifiers

ISSN

1618-2642

E-ISSN

1618-2650

DOI

10.1007/s00216-017-0542-0

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