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Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist rev...

Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist rev...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1930486673

Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase 3b study

About this item

Full title

Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase 3b study

Publisher

Tokyo: Springer Japan

Journal title

International journal of hematology, 2017-12, Vol.106 (6), p.777-786

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

Rapid vitamin K antagonist (VKA) reversal is required in patients experiencing major bleeding or requiring urgent surgery. Four-factor prothrombin complex concentrate (4F-PCC; Beriplex
®
/Kcentra
®
) was shown in two large randomized controlled, international phase 3b trials to be an effective alternative to plasma for urgent VKA revers...

Alternative Titles

Full title

Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase 3b study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1930486673

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1930486673

Other Identifiers

ISSN

0925-5710

E-ISSN

1865-3774

DOI

10.1007/s12185-017-2311-4

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