Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (I...
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)
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Publisher
New York: Springer New York
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Language
English
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Publisher
New York: Springer New York
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Contents
Stefan Mundlos, Darío Lupiáñez and colleagues investigate CNVs involving the regulatory landscape of
IHH
(Indian hedgehog), which cause craniosynostosis and synpolydactyly. Using genetic manipulation in mice, they show that
Ihh
is regulated by at least nine enhancers with individual tissue specificities and that duplications in this reg...
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Full title
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)
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TN_cdi_proquest_miscellaneous_1933229359
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1933229359
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3939