Alternative evolutionary histories in the sequence space of an ancient protein
Alternative evolutionary histories in the sequence space of an ancient protein
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Combining ancestral protein reconstruction with deep mutational scanning to characterize alternative histories in the sequence space around an ancient transcription factor reveals hundreds of alternative protein sequences that use diverse biochemical mechanisms to perform the derived function at least as well as the historical outcome.
The myria...
Alternative Titles
Full title
Alternative evolutionary histories in the sequence space of an ancient protein
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Author / Creator
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TN_cdi_proquest_miscellaneous_1938852831
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1938852831
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature23902
