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MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1940188176

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

About this item

Full title

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2017-10, Vol.19 (10), p.1237-1247

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

TNF is a master proinflammatory cytokine whose pathogenic role in inflammatory disorders can, in certain conditions, be attributed to RIPK1 kinase-dependent cell death. Survival, however, is the default response of most cells to TNF stimulation, indicating that cell demise is normally actively repressed and that specific checkpoints must be turned...

Alternative Titles

Full title

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1940188176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1940188176

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3608

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