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The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunother...

The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunother...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19412448

The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunotherapy strategies against glioblastoma?

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Full title

The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunotherapy strategies against glioblastoma?

Journal title

Human gene therapy, 2008-10, Vol.19 (10), p.1140-1140

Language

English

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Scope and Contents

Contents

The CIR (chimeric immune receptor) technology is based on the redirection of immune effector cells toward a selected target using chimeric receptors that are linked directly to the signaling domain of the endogenous T cell receptor (TCR). Using this technology, we previously engineered a "1st generation" CIR targeting EGFRvIII mutant protein (MRI-C...

Alternative Titles

Full title

The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunotherapy strategies against glioblastoma?

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19412448

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19412448

Other Identifiers

ISSN

1043-0342

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