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Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimuma...

Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimuma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1942708230

Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: an open-label, non-inferiority, randomised clinical trial

About this item

Full title

Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: an open-label, non-inferiority, randomised clinical trial

Publisher

England: Elsevier Limited

Journal title

Annals of the rheumatic diseases, 2018-04, Vol.77 (4), p.484-487

Language

English

Formats

Publication information

Publisher

England: Elsevier Limited

More information

Scope and Contents

Contents

ObjectiveHigh adalimumab serum concentrations do not result in better response in patients with rheumatoid arthritis (RA), suggesting overexposure. We investigated whether patients with adalimumab concentrations >8 µg/mL can prolong their dosing interval by 50% without a clinically relevant change in disease activity.MethodsConsecutive patients wit...

Alternative Titles

Full title

Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: an open-label, non-inferiority, randomised clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1942708230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1942708230

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2017-211781

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