Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microsph...
Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells
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Publisher
Oxford: Elsevier Ltd
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Language
English
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Publisher
Oxford: Elsevier Ltd
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Contents
Dendritic cell (DC)-based immunotherapy has been hampered by the lack of suitable methods for antigen delivery. Here, we use biodegradable poly(
d,
l-lactide-
co-glycolide) microspheres (PLGA-MS) as carriers of peptides and proteins for antigen delivery to human monocyte-derived DC (MoDC). Compared to soluble proteins, MHC classes I and II...
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Full title
Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells
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Record Identifier
TN_cdi_proquest_miscellaneous_19440955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19440955
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2005.10.032