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Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microsph...

Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microsph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19440955

Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells

About this item

Full title

Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells

Publisher

Oxford: Elsevier Ltd

Journal title

Vaccine, 2006-03, Vol.24 (11), p.1847-1857

Language

English

Formats

Publication information

Publisher

Oxford: Elsevier Ltd

More information

Scope and Contents

Contents

Dendritic cell (DC)-based immunotherapy has been hampered by the lack of suitable methods for antigen delivery. Here, we use biodegradable poly(
d,
l-lactide-
co-glycolide) microspheres (PLGA-MS) as carriers of peptides and proteins for antigen delivery to human monocyte-derived DC (MoDC). Compared to soluble proteins, MHC classes I and II...

Alternative Titles

Full title

Encapsulation of proteins and peptides into biodegradable poly( d, l-lactide- co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19440955

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19440955

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2005.10.032

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