Exploring genome-wide DNA methylation patterns in Aicardi syndrome
Exploring genome-wide DNA methylation patterns in Aicardi syndrome
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Author / Creator
Piras, Ignazio S , Mills, Gabrielle , Llaci, Lorida , Naymik, Marcus , Ramsey, Keri , Belnap, Newell , Balak, Chris D , Jepsen, Wayne M , Szelinger, Szabolcs , Siniard, Ashley L , Lewis, Candace R , LaFleur, Madison , Richholt, Ryan F , De Both, Matt D , Avela, Kristiina , Rangasamy, Sampathkumar , Craig, David W , Narayanan, Vinodh , Järvelä, Irma , Huentelman, Matthew J and Schrauwen, Isabelle
Publisher
England: Future Medicine Ltd
Journal title
Language
English
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Publication information
Publisher
England: Future Medicine Ltd
Subjects
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Scope and Contents
Contents
To explore differential DNA methylation (DNAm) in Aicardi syndrome (AIC), a severe neurodevelopmental disorder with largely unknown etiology.
We characterized DNAm in AIC female patients and parents using the Illumina 450 K array. Differential DNAm was assessed using the local outlier factor algorithm, and results were validated via qPCR in a la...
Alternative Titles
Full title
Exploring genome-wide DNA methylation patterns in Aicardi syndrome
Authors, Artists and Contributors
Author / Creator
Mills, Gabrielle
Llaci, Lorida
Naymik, Marcus
Ramsey, Keri
Belnap, Newell
Balak, Chris D
Jepsen, Wayne M
Szelinger, Szabolcs
Siniard, Ashley L
Lewis, Candace R
LaFleur, Madison
Richholt, Ryan F
De Both, Matt D
Avela, Kristiina
Rangasamy, Sampathkumar
Craig, David W
Narayanan, Vinodh
Järvelä, Irma
Huentelman, Matthew J
Schrauwen, Isabelle
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1945716576
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1945716576
Other Identifiers
ISSN
1750-1911
E-ISSN
1750-192X
DOI
10.2217/epi-2017-0060
