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A responsive MRI contrast agent to monitor functional cell status

A responsive MRI contrast agent to monitor functional cell status

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19461708

A responsive MRI contrast agent to monitor functional cell status

About this item

Full title

A responsive MRI contrast agent to monitor functional cell status

Publisher

United States: Elsevier Inc

Journal title

NeuroImage (Orlando, Fla.), 2006-09, Vol.32 (3), p.1142-1149

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

It has been shown that insoluble Gd chelates are suitable MRI contrast agents for conditional activation by intracellular lipases. The DTPA-based, insoluble, inactive contrast agent was internalized into dendritic cells by phagocytosis. Cleavage of long aliphatic side chains by intracellular lipase activity leads to the contrast agents solubility a...

Alternative Titles

Full title

A responsive MRI contrast agent to monitor functional cell status

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19461708

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19461708

Other Identifiers

ISSN

1053-8119

E-ISSN

1095-9572

DOI

10.1016/j.neuroimage.2006.05.009

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