A responsive MRI contrast agent to monitor functional cell status
A responsive MRI contrast agent to monitor functional cell status
About this item
Full title
Author / Creator
Himmelreich, U. , Aime, S. , Hieronymus, T. , Justicia, C. , Uggeri, F. , Zenke, M. and Hoehn, M.
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
It has been shown that insoluble Gd chelates are suitable MRI contrast agents for conditional activation by intracellular lipases. The DTPA-based, insoluble, inactive contrast agent was internalized into dendritic cells by phagocytosis. Cleavage of long aliphatic side chains by intracellular lipase activity leads to the contrast agents solubility a...
Alternative Titles
Full title
A responsive MRI contrast agent to monitor functional cell status
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_19461708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19461708
Other Identifiers
ISSN
1053-8119
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2006.05.009