Preassembly and ligand-induced restructuring of the chains of the IFN-γ receptor complex: the roles...
Preassembly and ligand-induced restructuring of the chains of the IFN-γ receptor complex: the roles of Jak kinases, Stat1 and the receptor chains
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We previously demonstrated using noninvasive technologies that the interferon-gamma (IFN-γ) receptor complex is preassembled
1
. In this report we determined how the receptor complex is preassembled and how the ligand-mediated conformational changes occur. The interaction of Stat1 with IFN-γR1 results in a conformational change localized to I...
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Preassembly and ligand-induced restructuring of the chains of the IFN-γ receptor complex: the roles of Jak kinases, Stat1 and the receptor chains
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TN_cdi_proquest_miscellaneous_19475843
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19475843
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1001-0602
E-ISSN
1748-7838
DOI
10.1038/sj.cr.7310008
