Effects of endogenous hypercortisolism on bone mRNA and microRNA expression in humans
Effects of endogenous hypercortisolism on bone mRNA and microRNA expression in humans
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Publisher
London: Springer London
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Language
English
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London: Springer London
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Summary
Hypercortisolism in humans suppresses osteoblastogenesis and osteoblast function through the upregulation of Wnt-signaling antagonists (sclerostin, Dkk1) and changes in microRNAs levels (miR-125b-5p, miR-218-5p, miR-34a-5p, miR-188-3p, miR-199a-5p) which are associated with mesenchymal stem-cell commitment to adipocytes or cartilage cell...
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Full title
Effects of endogenous hypercortisolism on bone mRNA and microRNA expression in humans
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TN_cdi_proquest_miscellaneous_1947615946
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1947615946
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ISSN
0937-941X
E-ISSN
1433-2965
DOI
10.1007/s00198-017-4241-7
