Control of cell polarity and motility by the PtdIns(3,4,5)P[sub]3 phosphatase SHIP1
Control of cell polarity and motility by the PtdIns(3,4,5)P[sub]3 phosphatase SHIP1
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Author / Creator
Nishio, Miki , Watanabe, Ken-Ichi , Sasaki, Junko , Taya, Choji , Takasuga, Shunsuke , Ryota IIzuka , Balla, Tamas , Yamazaki, Masakazu , Watanabe, Hiroshi , Itoh, Reietsu , Kuroda, Shoko , Horie, Yasuo , Foerster, Irmgard , Mak, Tak W , Yonekawa, Hiromichi , Penninger, Josef M , Kanaho, Yasunori , Suzuki, Akira and Sasaki, Takehiko
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English
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Contents
Proper neutrophil migration into inflammatory sites ensures host defense without tissue damage. Phosphoinositide 3-kinase (PI(3)K) and its lipid product phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P[sub]3) regulate cell migration, but the role of PtdIns(3,4,5)P[sub]3-degrading enzymes in this process is poorly understood. Here, we show t...
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Full title
Control of cell polarity and motility by the PtdIns(3,4,5)P[sub]3 phosphatase SHIP1
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Record Identifier
TN_cdi_proquest_miscellaneous_19492149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19492149
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1515
