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Serum concentrations of venlafaxine and its metabolites O-desmethylvenlafaxine and N-desmethylvenlaf...

Serum concentrations of venlafaxine and its metabolites O-desmethylvenlafaxine and N-desmethylvenlaf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19534223

Serum concentrations of venlafaxine and its metabolites O-desmethylvenlafaxine and N-desmethylvenlafaxine in heterozygous carriers of the CYP2D63, 4 or 5 allele

About this item

Full title

Serum concentrations of venlafaxine and its metabolites O-desmethylvenlafaxine and N-desmethylvenlafaxine in heterozygous carriers of the CYP2D63, 4 or 5 allele

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

European journal of clinical pharmacology, 2008-05, Vol.64 (5), p.483-487

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Objective
Increased systemic exposure of the antidepressant venlafaxine and increased risk of side effects has previously been observed in patients with defective CYP2D6 function [poor metabolisers (PMs)]. The aim of this study was to evaluate venlafaxine pharmacokinetics in carriers of one functional and one defective
CYP2D6
allele [heter...

Alternative Titles

Full title

Serum concentrations of venlafaxine and its metabolites O-desmethylvenlafaxine and N-desmethylvenlafaxine in heterozygous carriers of the CYP2D63, 4 or 5 allele

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19534223

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19534223

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-007-0453-7

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