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Research Article: CTL response compensation for the loss of an immunodominant class I-restricted HSV...

Research Article: CTL response compensation for the loss of an immunodominant class I-restricted HSV...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19540738

Research Article: CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

About this item

Full title

Research Article: CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

Journal title

Immunology and cell biology, 2006-12, Vol.84 (6), p.543-550

Language

English

Formats

Subjects

Subjects and topics

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Scope and Contents

Contents

The T-cell response to even complex pathogens is often focused on only a handful of immunodominant determinants. Such narrow responses provoke a selective pressure that can drive the emergence of CTL escape variants, raising the question of whether a broader response, targeting multiple non-dominant peptides may be more beneficial. To examine the a...

Alternative Titles

Full title

Research Article: CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_19540738

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19540738

Other Identifiers

ISSN

0818-9641

E-ISSN

1440-1711

DOI

10.1111/j.1440-1711.2006.01469.x

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