Estimating the causal tissues for complex traits and diseases
Estimating the causal tissues for complex traits and diseases
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
This study presents a new approach to estimate the tissues contributing to the genetic causality for complex traits and diseases. The method assesses tissue sharing of eQTLs among 44 tissues and then uses these tissue-sharing estimates to infer the tissues where trait-associated variants likely exert their function.
How to interpret the biologic...
Alternative Titles
Full title
Estimating the causal tissues for complex traits and diseases
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TN_cdi_proquest_miscellaneous_1954433836
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1954433836
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3981