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Estimating the causal tissues for complex traits and diseases

Estimating the causal tissues for complex traits and diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1954433836

Estimating the causal tissues for complex traits and diseases

About this item

Full title

Estimating the causal tissues for complex traits and diseases

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2017-12, Vol.49 (12), p.1676-1683

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This study presents a new approach to estimate the tissues contributing to the genetic causality for complex traits and diseases. The method assesses tissue sharing of eQTLs among 44 tissues and then uses these tissue-sharing estimates to infer the tissues where trait-associated variants likely exert their function.
How to interpret the biologic...

Alternative Titles

Full title

Estimating the causal tissues for complex traits and diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1954433836

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1954433836

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.3981

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