A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress
A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
Regulated exocytosis by secretory organelles is important for malaria parasite invasion and egress. Many parasite effector proteins, including perforins, adhesins, and proteases, are extensively proteolytically processed both pre- and postexocytosis. Here we report the multistage antiplasmodial activity of the aspartic protease inhibitor hydroxyl-e...
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Full title
A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress
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Record Identifier
TN_cdi_proquest_miscellaneous_1957461476
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1957461476
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf8675
