Preclinical mouse solid tumour models: status quo, challenges and perspectives
Preclinical mouse solid tumour models: status quo, challenges and perspectives
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
A systematic survey of 949 studies published in 2016 was conducted to quantitatively review the status quo of mouse tumour model experimentation.
The vast majority of
in vivo
studies relied on reductionist cell line-based models. More advanced models such as patient-derived xenograft, genetically engineered mouse and environm...
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Full title
Preclinical mouse solid tumour models: status quo, challenges and perspectives
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TN_cdi_proquest_miscellaneous_1957487985
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1957487985
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc.2017.92
