Tumour heterogeneity and resistance to cancer therapies
Tumour heterogeneity and resistance to cancer therapies
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Genomic instability fosters genetic diversity by providing the raw material for the generation of tumour heterogeneity
Tumours with high levels of intratumoural heterogeneity might predispose patients to inferior clinical outcomes
Under therapeutic selective pressure, resistance to treatment can emerge as a result of the expansi...
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Full title
Tumour heterogeneity and resistance to cancer therapies
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TN_cdi_proquest_miscellaneous_1961861362
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1961861362
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2017.166