Regeneration of the entire human epidermis using transgenic stem cells
Regeneration of the entire human epidermis using transgenic stem cells
About this item
Full title
Author / Creator
Hirsch, Tobias , Rothoeft, Tobias , Teig, Norbert , Bauer, Johann W. , Pellegrini, Graziella , De Rosa, Laura , Scaglione, Davide , Reichelt, Julia , Klausegger, Alfred , Kneisz, Daniela , Romano, Oriana , Secone Seconetti, Alessia , Contin, Roberta , Enzo, Elena , Jurman, Irena , Carulli, Sonia , Jacobsen, Frank , Luecke, Thomas , Lehnhardt, Marcus , Fischer, Meike , Kueckelhaus, Maximilian , Quaglino, Daniela , Morgante, Michele , Bicciato, Silvio , Bondanza, Sergio and De Luca, Michele
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused by mutations in genes encoding the basement membrane component laminin-332. Surviving patients with JEB develop chronic wounds to the skin and mucosa, which impair their quality of life and lead to skin cancer. Here we show that autologous transgenic keratino...
Alternative Titles
Full title
Regeneration of the entire human epidermis using transgenic stem cells
Authors, Artists and Contributors
Author / Creator
Rothoeft, Tobias
Teig, Norbert
Bauer, Johann W.
Pellegrini, Graziella
De Rosa, Laura
Scaglione, Davide
Reichelt, Julia
Klausegger, Alfred
Kneisz, Daniela
Romano, Oriana
Secone Seconetti, Alessia
Contin, Roberta
Enzo, Elena
Jurman, Irena
Carulli, Sonia
Jacobsen, Frank
Luecke, Thomas
Lehnhardt, Marcus
Fischer, Meike
Kueckelhaus, Maximilian
Quaglino, Daniela
Morgante, Michele
Bicciato, Silvio
Bondanza, Sergio
De Luca, Michele
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1965249271
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1965249271
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature24487
