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Vasohibins encode tubulin detyrosinating activity

Vasohibins encode tubulin detyrosinating activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1966235215

Vasohibins encode tubulin detyrosinating activity

About this item

Full title

Vasohibins encode tubulin detyrosinating activity

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6369), p.1453-1456

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Tubulin is subjected to a number of posttranslational modifications to generate heterogeneous microtubules. The modifications include removal and ligation of the C-terminal tyrosine of α-tubulin. The enzymes responsible for detyrosination, an activity first observed 40 years ago, have remained elusive. We applied a genetic screen in haploid human c...

Alternative Titles

Full title

Vasohibins encode tubulin detyrosinating activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1966235215

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1966235215

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aao5676

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