The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination aga...
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-g response
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English
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T helper type-1 response is essential to control Mycobacterium tuberculosis (MTB) infection but excessive antigen-mediated inflammation concurs to pathology. In mice challenged with MTB, the protection elicited by an Ag85B-encoding DNA vaccine, was lost when mice were boosted with Ag85B- protein in the absence of adjuvant. This effect was due to th...
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Full title
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-g response
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TN_cdi_proquest_miscellaneous_19690081
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19690081
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2008.05.050
