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Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity...

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1973021339

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

About this item

Full title

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

Publisher

London: Nature Publishing Group UK

Journal title

Prostate cancer and prostatic diseases, 2018-04, Vol.21 (1), p.113-125

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Immune checkpoint blockade has shown promising antitumor activity against a variety of tumor types. However, responses in castration-resistant prostate cancer remain relatively rare—potentially due to low baseline levels of infiltration. Using an immunocompetent cMyc-driven model (Myc-CaP), we sought to understand the immune infiltrat...

Alternative Titles

Full title

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1973021339

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1973021339

Other Identifiers

ISSN

1365-7852

E-ISSN

1476-5608

DOI

10.1038/s41391-017-0013-x

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