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Electron cryo-microscopy structure of a human TRPM4 channel

Electron cryo-microscopy structure of a human TRPM4 channel

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1974012775

Electron cryo-microscopy structure of a human TRPM4 channel

About this item

Full title

Electron cryo-microscopy structure of a human TRPM4 channel

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-12, Vol.552 (7684), p.200-204

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ca
2+
-activated, non-selective (CAN) ion channels sense increases of the intracellular Ca
2+
concentration, producing a flux of Na
+
and/or K
+
ions that depolarizes the cell, thus modulating cellular Ca
2+
entry. CAN channels are involved in cellular responses such as neuronal bursting activity and cardiac rhythm. He...

Alternative Titles

Full title

Electron cryo-microscopy structure of a human TRPM4 channel

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1974012775

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1974012775

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature24674

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