Electron cryo-microscopy structure of a human TRPM4 channel
Electron cryo-microscopy structure of a human TRPM4 channel
About this item
Full title
Author / Creator
Winkler, Paige A. , Huang, Yihe , Sun, Weinan , Du, Juan and Lü, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Ca
2+
-activated, non-selective (CAN) ion channels sense increases of the intracellular Ca
2+
concentration, producing a flux of Na
+
and/or K
+
ions that depolarizes the cell, thus modulating cellular Ca
2+
entry. CAN channels are involved in cellular responses such as neuronal bursting activity and cardiac rhythm. He...
Alternative Titles
Full title
Electron cryo-microscopy structure of a human TRPM4 channel
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Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1974012775
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1974012775
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature24674