Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity
Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity
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Publisher
Berlin: Springer
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Language
English
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Berlin: Springer
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Contents
Glutathione S-transferases (GSTs) are involved in the detoxification of xenobiotics, such as several cytostatic drugs, through conjugation with glutathione (GSH). Pi class GST (GST P) liver expression is associated with preneoplastic and neoplastic development and contributes with the drug-resistance phenotype. Ethacrynic acid (EA) is an inhibitor...
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Full title
Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity
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TN_cdi_proquest_miscellaneous_19749566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19749566
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ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-007-0183-8
