Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated...
Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials
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Author / Creator
Modjarrad, Kayvon , Lin, Leyi , George, Sarah L , Stephenson, Kathryn E , Eckels, Kenneth H , De La Barrera, Rafael A , Jarman, Richard G , Sondergaard, Erica , Tennant, Janice , Ansel, Jessica L , Mills, Kristin , Koren, Michael , Robb, Merlin L , Barrett, Jill , Thompson, Jason , Kosel, Alison E , Dawson, Peter , Hale, Andrew , Tan, C Sabrina , Walsh, Stephen R , Meyer, Keith E , Brien, James , Crowell, Trevor A , Blazevic, Azra , Mosby, Karla , Larocca, Rafael A , Abbink, Peter , Boyd, Michael , Bricault, Christine A , Seaman, Michael S , Basil, Anne , Walsh, Melissa , Tonwe, Veronica , Hoft, Daniel F , Thomas, Stephen J , Barouch, Dan H and Michael, Nelson L
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that showed protection in mice and non-human primates against viraemia after Zika virus challenge. Here we present the preliminary results in human beings.
We did three phase 1,...
Alternative Titles
Full title
Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials
Authors, Artists and Contributors
Author / Creator
Lin, Leyi
George, Sarah L
Stephenson, Kathryn E
Eckels, Kenneth H
De La Barrera, Rafael A
Jarman, Richard G
Sondergaard, Erica
Tennant, Janice
Ansel, Jessica L
Mills, Kristin
Koren, Michael
Robb, Merlin L
Barrett, Jill
Thompson, Jason
Kosel, Alison E
Dawson, Peter
Hale, Andrew
Tan, C Sabrina
Walsh, Stephen R
Meyer, Keith E
Brien, James
Crowell, Trevor A
Blazevic, Azra
Mosby, Karla
Larocca, Rafael A
Abbink, Peter
Boyd, Michael
Bricault, Christine A
Seaman, Michael S
Basil, Anne
Walsh, Melissa
Tonwe, Veronica
Hoft, Daniel F
Thomas, Stephen J
Barouch, Dan H
Michael, Nelson L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1975015864
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1975015864
Other Identifiers
ISSN
0140-6736,1474-547X
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(17)33106-9