Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The crystal structure of the complement receptor C5aR1 bound to a small-molecule antagonist provides insights into this receptor class and how they could be better targeted therapeutically.
Structure of a complement receptor
The complement system plays a central part in innate immune responses and provides a basic defence mechanism against in...
Alternative Titles
Full title
Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
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Record Identifier
TN_cdi_proquest_miscellaneous_1984750974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1984750974
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25025
