A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal ca...
A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In this protocol, mouse or human colorectal cancer organoids are transplanted into the cecal epithelium. The transplanted organoids grow into a single primary tumor mass within the intestinal tract and tumor cells are capable of metastasis.
Most currently available colorectal cancer (CRC) mouse models are not suitable for studying progression to...
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Full title
A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression
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TN_cdi_proquest_miscellaneous_1984751665
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1984751665
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/nprot.2017.137
