NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and...
NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways
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Author / Creator
Zhuang, Yuchen , Han, Changxu , Li, Bing , Jin, Liang , Dang, Erle , Fang, Hui , Qiao, Hongjiang and Wang, Gang
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Keratin-17 (K17) is a cytoskeletal protein produced by keratinocytes (KCs), which is overexpressed in psoriasis and may play a pivotal role in its pathogenesis. Narrow-band ultraviolet B (NB-UVB) irradiation is used as a general treatment for psoriasis, although its impact on K17 expression has yet to be determined. In this study, we aimed to inves...
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Full title
NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways
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Record Identifier
TN_cdi_proquest_miscellaneous_1989600298
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1989600298
Other Identifiers
ISSN
0340-3696
E-ISSN
1432-069X
DOI
10.1007/s00403-018-1812-1