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NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and...

NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1989600298

NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways

About this item

Full title

NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of Dermatological Research, 2018-03, Vol.310 (2), p.147-156

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Keratin-17 (K17) is a cytoskeletal protein produced by keratinocytes (KCs), which is overexpressed in psoriasis and may play a pivotal role in its pathogenesis. Narrow-band ultraviolet B (NB-UVB) irradiation is used as a general treatment for psoriasis, although its impact on K17 expression has yet to be determined. In this study, we aimed to inves...

Alternative Titles

Full title

NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1989600298

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1989600298

Other Identifiers

ISSN

0340-3696

E-ISSN

1432-069X

DOI

10.1007/s00403-018-1812-1

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