Building and decoding ubiquitin chains for mitophagy
Building and decoding ubiquitin chains for mitophagy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The serine/threonine-protein kinase PINK1, mitochondrial and the E3 ubiquitin-protein ligase parkin form a signal transduction pathway that marks damaged mitochondria with ubiquitin chains to promote mitophagy. Understanding this pathway is important, as it crucial for several physiological processes and, when defective, it is associa...
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Full title
Building and decoding ubiquitin chains for mitophagy
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TN_cdi_proquest_miscellaneous_1990489161
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1990489161
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2017.129
