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Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection

Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1990854125

Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection

About this item

Full title

Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Journal of molecular medicine (Berlin, Germany), 2018-04, Vol.96 (3-4), p.237-247

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Pyruvate carboxylase (PC), an anaplerotic enzyme, plays an essential role in various cellular metabolic pathways including gluconeogenesis, de novo fatty acid synthesis, amino acid synthesis, and glucose-induced insulin secretion. Deregulation of PC expression or activity has long been known to be associated with metabolic syndrome in several roden...

Alternative Titles

Full title

Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1990854125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1990854125

Other Identifiers

ISSN

0946-2716

E-ISSN

1432-1440

DOI

10.1007/s00109-018-1622-0

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