Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Purpose
L-Histidine (L-His) and polysorbate 20 (PS20) are two excipients frequently included in parenteral products to stabilize biotherapeutics. The objective of the current work was to investigate the impact of L-His on PS20 stability in aqueous solutions when subjected to forced oxidation and accelerated stability testing.
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The s...
Alternative Titles
Full title
Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
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TN_cdi_proquest_miscellaneous_1991180884
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1991180884
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-017-2321-1
