Regulatory and biosynthetic effects of the bkd gene clusters on the production of daptomycin and its...
Regulatory and biosynthetic effects of the bkd gene clusters on the production of daptomycin and its analogs A21978C1–3
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Cham: Oxford University Press
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English
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Cham: Oxford University Press
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Abstract
Daptomycin is a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus in an acidic peptide complex A21978C. In this complex, A21978C1–3 is most abundant and contains branched-chain fatty acyl groups, while daptomycin has a straight decanoic acyl group. The branched-chain α-keto acid dehydrogenase complex (BCDH complex), enc...
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Regulatory and biosynthetic effects of the bkd gene clusters on the production of daptomycin and its analogs A21978C1–3
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TN_cdi_proquest_miscellaneous_1999200325
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999200325
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ISSN
1367-5435
E-ISSN
1476-5535
DOI
10.1007/s10295-018-2011-y
