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Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolutio...

Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolutio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999678749

Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C

About this item

Full title

Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2018-03, Vol.13 (3), p.459-477

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This protocol describes targeted chromatin capture (T2C), a high-resolution method to interrogate 3D chromatin organization and genomic interactions at sub-kilobase-pair resolution that requires minimal cell numbers and sequencing depth.
Chromosome conformation capture (3C) and its derivatives (e.g., 4C, 5C and Hi-C) are used to analyze the 3D o...

Alternative Titles

Full title

Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1999678749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999678749

Other Identifiers

ISSN

1754-2189,1750-2799

E-ISSN

1750-2799

DOI

10.1038/nprot.2017.132

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