SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data
SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
We have developed a new method, SOAPfuse, to identify fusion transcripts from paired-end RNA-Seq data. SOAPfuse applies an improved partial exhaustion algorithm to construct a library of fusion junction sequences, which can be used to efficiently identify fusion events, and employs a series of filters to nominate high-confidence fusion transcripts. Compared with other released tools, SOAPfuse achieves higher detection efficiency and consumed less computing resources. We applied SOAPfuse to RNA-Seq data from two bladder cancer cell lines, and confirmed 15 fusion transcripts, including several novel events common to both cell lines. SOAPfuse is available at
http://soap.genomics.org.cn/soapfuse.html
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Full title
SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data
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Record Identifier
TN_cdi_proquest_miscellaneous_1999945343
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999945343
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ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/gb-2013-14-2-r12
