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Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sens...

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sens...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999960170

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

About this item

Full title

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

Publisher

England

Journal title

Genome biology, 2014-03, Vol.15 (3), p.R47-R47, Article R47

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

We demonstrate a method for the prediction of chemotherapeutic response in patients using only before-treatment baseline tumor gene expression data. First, we fitted models for whole-genome gene expression against drug sensitivity in a large panel of cell lines, using a method that allows every gene to influence the prediction. Following data homog...

Alternative Titles

Full title

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1999960170

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1999960170

Other Identifiers

ISSN

1474-760X

E-ISSN

1474-760X

DOI

10.1186/gb-2014-15-3-r47

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