Diverse modes of genomic alteration in hepatocellular carcinoma
Diverse modes of genomic alteration in hepatocellular carcinoma
About this item
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Author / Creator
Jhunjhunwala, Suchit , Jiang, Zhaoshi , Stawiski, Eric W , Gnad, Florian , Liu, Jinfeng , Mayba, Oleg , Du, Pan , Diao, Jingyu , Johnson, Stephanie , Wong, Kwong-Fai , Gao, Zhibo , Li, Yingrui , Wu, Thomas D , Kapadia, Sharookh B , Modrusan, Zora , French, Dorothy M , Luk, John M , Seshagiri, Somasekar and Zhang, Zemin
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Hepatocellular carcinoma (HCC) is a heterogeneous disease with high mortality rate. Recent genomic studies have identified TP53, AXIN1, and CTNNB1 as the most frequently mutated genes. Lower frequency mutations have been reported in ARID1A, ARID2 and JAK1. In addition, hepatitis B virus (HBV) integrations into the human genome have been associated...
Alternative Titles
Full title
Diverse modes of genomic alteration in hepatocellular carcinoma
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Record Identifier
TN_cdi_proquest_miscellaneous_2000277663
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000277663
Other Identifiers
ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/s13059-014-0436-9
