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Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000329698

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

About this item

Full title

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6173), p.881-885

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Flaviviruses, the human pathogens responsible for dengue fever, West Nile fever, tick-borne encephalitis, and yellow fever, are endemic in tropical and temperate parts of the world. The flavivirus nonstructural protein 1 (NS1) functions in genome replication as an intracellular dimer and in immune system evasion as a secreted hexamer. We report cry...

Alternative Titles

Full title

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2000329698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000329698

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1247749

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