A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs
A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs
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United States: American Association for the Advancement of Science
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English
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United States: American Association for the Advancement of Science
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During limb development, the time a nd place of
Hox
transcription are fixed by respective gene position within the gene cluster.
Andrey
et al.
(p.
1234167
; see the Perspective by
Rodrigues and Tabin
) found that this enigmatic property results from the opposite and successive actions of two large regulatory landscapes lo...
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A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs
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TN_cdi_proquest_miscellaneous_2000371289
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2000371289
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0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1234167