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Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium

Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2001061177

Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium

About this item

Full title

Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6375), p.563-567

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Classically, it is thought that citrate synthase only works in one direction: to catalyze the production of citrate from acetyl coenzyme A and oxaloacetate in the tricarboxylic acid (TCA) cycle. The TCA cycle can run in reverse to cleave citrate and fix carbon dioxide autotrophically, but this was thought to occur only with alternative enzymes, suc...

Alternative Titles

Full title

Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2001061177

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2001061177

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aao2410

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