Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium
Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium
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United States: The American Association for the Advancement of Science
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English
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United States: The American Association for the Advancement of Science
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Classically, it is thought that citrate synthase only works in one direction: to catalyze the production of citrate from acetyl coenzyme A and oxaloacetate in the tricarboxylic acid (TCA) cycle. The TCA cycle can run in reverse to cleave citrate and fix carbon dioxide autotrophically, but this was thought to occur only with alternative enzymes, suc...
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Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium
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TN_cdi_proquest_miscellaneous_2001061177
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2001061177
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aao2410