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NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human l...

NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20011866

NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2

About this item

Full title

NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2

Publisher

Boston: Springer US

Journal title

Investigational new drugs, 2008-04, Vol.26 (2), p.111-118

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Summary
It has been demonstrated that substance P (SP) induces cell proliferation and neurokinin-1 (NK-1) receptor antagonists inhibit growth in several human cancer cell lines, but it is currently unknown whether such actions are exerted on human laryngeal carcinoma cell line HEp-2. In addition, the presence of NK-1 receptor has not been demons...

Alternative Titles

Full title

NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_20011866

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20011866

Other Identifiers

ISSN

0167-6997

E-ISSN

1573-0646

DOI

10.1007/s10637-007-9087-y

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