Hippocampal ripples down-regulate synapses
Hippocampal ripples down-regulate synapses
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Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: The American Association for the Advancement of Science
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Contents
The specific effects of sleep on synaptic plasticity remain unclear. We report that mouse hippocampal sharp-wave ripple oscillations serve as intrinsic events that trigger long-lasting synaptic depression. Silencing of sharp-wave ripples during slow-wave states prevented the spontaneous down-regulation of net synaptic weights and impaired the learn...
Alternative Titles
Full title
Hippocampal ripples down-regulate synapses
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Record Identifier
TN_cdi_proquest_miscellaneous_2002213276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2002213276
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aao0702
