Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and h...
Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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This protocol adapts traditional ChIP-seq for the detection of DNA secondary structures through the use of a G4-structure-specific single-chain antibody. This enables the determination of G4 structure formation genome-wide in chromatin.
G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and are linked to fundament...
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Full title
Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
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TN_cdi_proquest_miscellaneous_2007978174
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2007978174
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/nprot.2017.150
