Transforming growth factor-β1 induces cerebrovascular dysfunction and astrogliosis through angiotens...
Transforming growth factor-β1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor-mediated signaling pathways
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Publisher
Canada: NRC Research Press
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Language
English
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Publisher
Canada: NRC Research Press
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Contents
Transgenic mice constitutively overexpressing the cytokine transforming growth factor-β1 (TGF-β1) (TGF mice) display cerebrovascular alterations as seen in Alzheimer’s disease (AD) and vascular cognitive impairment and dementia (VCID), but no or only subtle cognitive deficits. TGF-β1 may exert part of its deleterious effects through interactions wi...
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Full title
Transforming growth factor-β1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor-mediated signaling pathways
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TN_cdi_proquest_miscellaneous_2011274194
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2011274194
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ISSN
0008-4212
E-ISSN
1205-7541
DOI
10.1139/cjpp-2017-0640