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Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2013515375

Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

About this item

Full title

Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Histochemistry and cell biology, 2018-06, Vol.149 (6), p.635-644

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

SPINT1, also known as HAI-1, is a Kunitz-type serine protease inhibitor that inhibits multiple proteases including hepatocyte growth factor (HGF) activator and matriptase. SPINT1 has been shown to modulate HGF/MET activation in certain cancer types. In the present study, we analyzed microarray datasets and found that SPINT1 was consistently upregul...

Alternative Titles

Full title

Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2013515375

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2013515375

Other Identifiers

ISSN

0948-6143

E-ISSN

1432-119X

DOI

10.1007/s00418-018-1660-2

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