Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus h...
Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy
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Netherlands: Elsevier Ltd
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Language
English
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Netherlands: Elsevier Ltd
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Highlights•Analysis of a plant made VLP vaccine candidate using cryo-EM and tomography. •99.9% of the HA trimers are on discoid and ovoid-shaped particles. •VLPs remain structurally stable for over 12 months while kept at 4 °C. •VLPs bind to plasma membrane and are internalized similarly to intact virus. •Mouse dendritic cells undergo morphological...
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Full title
Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy
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TN_cdi_proquest_miscellaneous_2015411204
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2015411204
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2018.02.106
