Synergistic drug combinations tend to improve therapeutically relevant selectivity
Synergistic drug combinations tend to improve therapeutically relevant selectivity
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Although combinations of drugs are often more potent than single agents, they are also believed to induce worse side effects. By screening >94,000 drug pairs
in vitro
, Lehár
et al
. show that synergistic combinations tend to be more selective than single drugs and are therefore unlikely to cause synergistic side effects.
Drug combin...
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Full title
Synergistic drug combinations tend to improve therapeutically relevant selectivity
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TN_cdi_proquest_miscellaneous_20199165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20199165
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1549
