SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulatin...
SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival
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Author / Creator
Liu, J. Y. , Zeng, Q. H. , Cao, P. G. , Xie, D. , Yang, F. , He, L. Y. , Dai, Y. B. , Li, J. J. , Liu, X. M. , Zeng, H. L. , Fan, X. J. , Liu, L. , Zhu, Y. X. , Gong, L. , Cheng, Y. , Zhou, J. D. , Hu, J. , Bo, H. , Xu, Z. Z. and Cao, K.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Sperm-associated antigen 5 (SPAG5) is involved in various biological processes. However, the roles of SPAG5 in bladder urothelial carcinoma (BUC) are unknown. This study showed that upregulation of SPAG5 was detected frequently in primary BUC tissues, and was associated with significantly worse survival among the 112 patients that underwent radical...
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Full title
SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival
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TN_cdi_proquest_miscellaneous_2026422196
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2026422196
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0223-2