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Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity

Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2032402740

Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity

About this item

Full title

Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity

Publisher

New York: Springer US

Journal title

Molecular neurobiology, 2019-01, Vol.56 (1), p.321-334

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Mutations in genes affecting mitochondrial proteins are increasingly recognised in patients with epilepsy, but the factors determining cell fate during seizure activity in these mutations remain unknown. Fluorescent dye imaging techniques were applied to fibroblast cell lines from patients suffering from common mitochondrial mutations and to age-ma...

Alternative Titles

Full title

Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2032402740

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2032402740

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-018-1078-9

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